ea0016p12 | Adrenal | ECE2008
Appolloni Gloria
, Arnaldi Giorgio
, Di Stefano Michele
, Spegni Monica
, Cardinaletti Marina
, Trementino Laura
, Boscaro Marco
Background: The development of a vascular supply is a critical factor in the growth and metastatic spread of malignant tumors. The recognition of the vascular endothelial growth factor (VEGF) pathway as a key regulator of angiogenesis has led to a considerable efforts to exploit its potential for therapy in oncology. Endocrine gland-derived (EG-VEGF) has been recently identified as an endothelial cell mitogen, predominantly expressed in steroidogenic tissues; it represents a n...